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House dust spurs growth of fat cells in lab tests
"Characterization of Adipogenic Activity of House Dust Extracts and Semi-Volatile Indoor Contaminants in 3T3-L1 Cells"
Environmental Science & Technology
Poor diet and a lack of physical activity are major contributors to the world’s obesity epidemic, but researchers have also identified common environmental pollutants that could play a role. Now one team reports in ACS’ journal Environmental Science & Technology that small amounts of house dust containing many of these compounds can spur fat cells to accumulate more triglycerides, or fat, in a lab dish.
Endocrine-disrupting chemicals, or EDCs, are synthetic or naturally occurring compounds that can interfere with or mimic the body’s hormones. EDCs, such as flame retardants, phthalates and bisphenol-A, are known for their potential effects on reproductive, neurological and immune functions. But animal studies also suggest that early life exposure to some EDCs can cause weight gain later in life, and, as a result, have been called “obesogens.” Some manufacturers have reduced the use of EDCs in products, but many are still ubiquitous in consumer goods. And they wind up in indoor dust that can be inhaled, ingested, or absorbed through the skin. The U.S. Environmental Protection Agency estimates that children consume 50 milligrams of house dust each day. Concerned about the potential effects EDCs in dust might have on children’s health, Heather Stapleton and colleagues wanted to see if the compounds in house dust might have an effect on fat cells.
https://www.acs.org/content/acs/en/p...lab-tests.html
House dust spurs growth of fat cells in lab tests
"Characterization of Adipogenic Activity of House Dust Extracts and Semi-Volatile Indoor Contaminants in 3T3-L1 Cells"
Environmental Science & Technology
Poor diet and a lack of physical activity are major contributors to the world’s obesity epidemic, but researchers have also identified common environmental pollutants that could play a role. Now one team reports in ACS’ journal Environmental Science & Technology that small amounts of house dust containing many of these compounds can spur fat cells to accumulate more triglycerides, or fat, in a lab dish.
Endocrine-disrupting chemicals, or EDCs, are synthetic or naturally occurring compounds that can interfere with or mimic the body’s hormones. EDCs, such as flame retardants, phthalates and bisphenol-A, are known for their potential effects on reproductive, neurological and immune functions. But animal studies also suggest that early life exposure to some EDCs can cause weight gain later in life, and, as a result, have been called “obesogens.” Some manufacturers have reduced the use of EDCs in products, but many are still ubiquitous in consumer goods. And they wind up in indoor dust that can be inhaled, ingested, or absorbed through the skin. The U.S. Environmental Protection Agency estimates that children consume 50 milligrams of house dust each day. Concerned about the potential effects EDCs in dust might have on children’s health, Heather Stapleton and colleagues wanted to see if the compounds in house dust might have an effect on fat cells.
https://www.acs.org/content/acs/en/p...lab-tests.html
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